منابع مشابه
Opiate System Mediate the Antinociceptive Effects of Coriandrum sativum in Mice
Our previous study showed that Coriandrum sativum (CS) has antinociceptive effects, but the mechanisms that mediate this effect are not clear. The present study was designed to test the role of opiate system in the antinociceptive effects of CS on acute and chronic pain in mice using Hot Plate (HP), Tail Flick (TF) and Formalin (FT) tests and also to compare its effect with dexamethasone (DE...
متن کاملOpiate System Mediate the Antinociceptive Effects of Coriandrum sativum in Mice
Our previous study showed that Coriandrum sativum (CS) has antinociceptive effects, but the mechanisms that mediate this effect are not clear. The present study was designed to test the role of opiate system in the antinociceptive effects of CS on acute and chronic pain in mice using Hot Plate (HP), Tail Flick (TF) and Formalin (FT) tests and also to compare its effect with dexamethasone (DE...
متن کاملGenetic and pharmacological antagonism of NK1 receptor prevents opiate abuse potential
Development of an efficacious, non-addicting analgesic has been challenging. Discovery of novel mechanisms underlying addiction may present a solution. Here we target the neurokinin system, which is involved in both pain and addiction. Morphine exerts its rewarding actions, at least in part, by inhibiting GABAergic input onto substance P (SP) neurons in the ventral tegmental area (VTA), subsequ...
متن کاملPapaverine-induced mydriasis.
Five cases of ipsilateral pupillary dilatation that developed during local intraarterial infusion of papaverine are reported. All patients were being treated for symptomatic vasospasm secondary to subarachnoid hemorrhage. In each case, the tip of the infusion catheter was positioned in the internal carotid artery in close proximity to the ostium of the ophthalmic artery. Pupillary dilatation in...
متن کاملMigraine with unilateral mydriasis.
A 54-year-old, post-menopausal woman has had migraine headaches since the age of 40, occurring about once per month, responding well to sumatriptan. She experiences a stabbing pain in the left eye and left side of head, associated with nausea and vomiting. The pain has only affected her left side but a brain MRI was normal. She has an aura of blurred vision in the left eye alone, seeing images ...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 1981
ISSN: 0007-1188
DOI: 10.1111/j.1476-5381.1981.tb08732.x